Thiopurine S-methyltransferase (EC ...

Thiopurine S-methyltransferase (EC 2.1.1.67)[60µM]

Product Information

Product Overview:

Methylation of key biological molecules and proteins plays important roles in numerous biological systems, including signal transduction, biosynthesis, protein repair, gene silencing and chromatin regulation (1). The S-adenosylmethionine (SAM) dependent methyltransferases use SAM, the second most commonly used enzymatic cofactor after ATP. SAM, also known as AdoMet, acts as a donor of a methyl group that is required for the modification of proteins and DNA. Aberrant levels of SAM have been linked to many abnormalities, including Alzheimer’s, depression, Parkinson’s, multiple sclerosis, liver failure and cancer (2). Thiopurine S-methyltransferase transfer methyl groups for S-adenosylmethionine (SAM) to thiopurines. This enzymes is a highly purifed recombinant human Thiopurine S-methyltransferase, EC 2.1.1.67.

Catalog#: 786-426
LID#: 4415E
Quantity :
Order by Phone or Fax: 1.800.316.3081

Specifications

Warehouse Storage Temp-80C
DescriptionA recombinant SAM Methyltransferase
Unit Size0.5ml
Safety StatementsFor Research Use Only
Sample AvailabilityYes
SynonymSAM methyltransferase, TPMT, thiopurine, methyltransferase, thiopurine S-methyltransferase, 6-thiopurine S-methyltransferase, 6-thiopurine transmethylase, mercaptopurine methyltransferase, thiopurine methyltransferase, S-adenosyl-L-methionine, SAM

Shipping & Handling

Estimated Ship Time: 2 Business Days

Shipped In: Dry Ice, (Handling Fee : $ 20.00 USD)

Hazardous Material: No

Storage

Shelf Life: 12 MONTHS

Storage Temperature: -80C

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