TCEP; Tris (2-carboxymethyl) phosph...

TCEP; Tris (2-carboxymethyl) phosphine

Product Information

Product Overview:

TCEP is a water-soluble, odorless, non-toxic and stable protein reductant. This potent reducing agent is a popular alternative to ß-mercaptoethanol and DTT (dithiothreitol) use for most applications. The reduction potency of TCEP is twice as high as that of DTT, and TCEP is effective in reducing proteins over a wider range of pH conditions, including lower acidic pH ranges (pH 2-11), compared to other reductants. Since TCEP is a charged molecule, it cannot penetrate hydrophobic environments. Therefore, the use of a denaturant, acidic condition (pH 2.8-5) or basic condition (pH 9-11), is recommended for effective reduction. TCEP reduces stable disulfide bonds in less than 5 minutes at room temperature and is compatible with the protein alkylation reactions. For more reducing agents, click here. Click for TCEP Reducing Gel


Reduction of protein and peptide solutions


Chemical Name: tris(2-carboxyethyl)phosphine, HCl Synonym: TCEP, Hydrochloride CAS Number: 51805-45-9 Chemical Formula: C9H15O6P•HCl Molecular Weight: 286.65 Form: White crystalline solid Solubility: H2O (5mg/ml)

Catalog#: 786-030
LID#: 3991B
Quantity :
Order by Phone or Fax: 1.800.316.3081


Warehouse Storage Temp4C
DescriptionA potent protein reductant for a wide range of pH conditions
Unit Size1g
Safety StatementsFor Research Use Only
Sample AvailabilityYes
SynonymTCEP, carboxyethyl phosphine, protein reductant, reducing agent

Shipping & Handling

Estimated Ship Time: 2 Business Days

Shipped In: Ambient

Hazardous Material: No


Shelf Life: 12 MONTHS

Storage Temperature: 4C

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