anti-SUMO1 antibody

anti-SUMO1 antibody

As One International, Inc.

Product Information

Product Overview:

SUMO (Small Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. Unlike ubiquitination which targets proteins for degradation SUMO modification plays a critical role in a number of cellular functions including nucleocytoplasmic transport gene expression cell cycle and formation of subnuclear structures such as promyelocytic leukemia (PML) bodies. There are three confirmed SUMO isoforms in human; SUMO1 SUMO2 and SUMO3. SUMO2 /3 show a high degree of similarity to each other and are distinct from SUMO1. Individual SUMO family members are all targeted to different proteins with diverse biological functions. SUMO1 is conjugated to RanGAP PML p53 and IkappaB-alpha to regulate nuclear trafficking formation of subnuclear structures regulation of transcriptional activity and protein stability. SUMO1 is encoded as a 101 aa protein and first Met and C-terminal 4 aa are removed from the preprotein. The antibody was produced from the hybridoma cultured in serum-free medium and purified under mild conditions by propriety chromatography processes. Applications: WB, IF, IHC, ELISA

Application:

WB, IF, IHC, ELISA

Catalog#: 70-653
LID#: 3862A
Quantity :
Order by Phone or Fax: 1.800.316.3081
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Specifications

ClonalityPolyclonal
Raised InRat
ReactivityHuman, simian, mouse and rat
Gene IDP63165
Unit Size100 ug
Safety StatementsThis product is for research use only.
Sample AvailabilityNo

Shipping & Handling

Estimated Ship Time: 3 Business Days

Shipped In: Blue Ice

Hazardous Material: No

Storage

Storage Temperature: See datasheet

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