Product Overview:
E. coli RecA protein plays critically important roles in homologous recombination, recombination repair and regulation of cellular responses to DNA damage (SOS response). RecA promotes auto-cleavage of LexA repressor by its co-protease activity after DNA damage, and induces many proteins related to DNA repair, including RecA itself. The product was prepared by immunizing rabbit with the recombinant protein, which was over-expressed in E. coli, and highly purified by chromatography. Using this antiserum in Western blotting, the band of 38 kD corresponding to RecA was obtained from the extract of E. coli cells.