RIMS3 Antibody

RIMS3 Antibody

Product Information

Product Overview:

Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity. This antibody is predicted to have no cross-reactivity to other Rim proteins.

Catalog#: NBP1-76874
LID#: 171760A
Quantity :
Order by Phone or Fax: 1.800.316.3081

Specifications

Host SpeciesRabbit
SpeciesHuman, Mouse
Entrez Human ID9783
Preservation0.02% Sodium Azide
Species ReactivityHuman, Mouse
Swissprot Human IDNP_055562
Gene SymbolRIMS3
ApplicationsWB, ELISA, IHC, IHC-P
Species AbbreviationHu, Mu
Grade/PurityAffinity purified
ClonalityPolyclonal
ImmunogenAntibody was raised against a 17 amino acid peptide from near the amino terminus of human Rim3.
Storage BufferPBS
DilutionELISA 1:100-1:2000, Immunohistochemistry 1:10-1:2000, Immunohistochemistry-Paraffin 1:10-1:2000, Western Blot 1:100-1:2000
Unit Size0.1mg
Concentration1 mg/ml
Safety StatementsThis product is for research use only and is not approved for use in humans or in clinical diagnosis.
Sample AvailabilityYes
SynonymKIAA0237, KIAA0137, Nim3, NIM3Rab-3 interacting molecule 3, Rab-3-interacting molecule 3, regulating synaptic membrane exocytosis 3, regulating synaptic membrane exocytosis protein 3, RIM 3, RIM3, RIM3 gamma

Shipping & Handling

Estimated Ship Time: 3 Business Days

Shipped In: Blue Ice

Hazardous Material: No

Storage

Storage Temperature: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

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