RGS18 Antibody

RGS18 Antibody

Product Information

Product Overview:

Regulators of G-protein signaling (RGSs) are a protein family that can act as GTPase-activating proteins for G(alphai)- and G(alphaq)-class proteins. One of these proteins, RGS18, is a 235 amino acid protein that is closely related to RGS5 (46% identity) and approximately 30-40% identity to other RGS proteins. This protein is expressed in platelet, leukocyte, and megakaryocyte cell lines. Engagement of TLR3 or TLR4 on monocyte-derived DCs potently down-regulates RGS18 and RGS14 without modifying other RGS proteins. A similar pattern of RGS protein expression occurs in immature bone marrow-derived mouse DCs stimulated to mature via TLR4 signaling. The changes in RGS18 and RGS1 expression are likely important for DC function.

Catalog#: NB100-56734
LID#: 171661A
Quantity :
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Specifications

Host SpeciesRabbit
SpeciesHuman
ControlsLung, Spleen, or Bone marrow lysates.
Entrez Human ID64407
Preservation0.05% Sodium Azide
Species ReactivityCross reacts with Human. Predicted to react with Mouse and Rat.
Swissprot Human IDQ9NS28
Gene SymbolRGS18
ApplicationsWB
Species AbbreviationHu
Grade/PurityProtein G purified
ClonalityPolyclonal
ImmunogenAmino acids 200-218 of human RGS18 (Genebank accession no NP_570138). were used as immunogen.
Storage BufferPBS containing 0.05% BSA
DilutionWestern Blot 1-3 ug/ml
Gene ID7345
Unit Size0.1mg
Concentration0.5 mg/ml
Safety StatementsThis product is for research use only and is not approved for use in humans or in clinical diagnosis.
Sample AvailabilityYes
Synonymregulator of G-protein signalling 13, regulator of G-protein signaling 18, RGS13regulator of G-protein signalling 18

Shipping & Handling

Estimated Ship Time: 3 Business Days

Shipped In: Blue Ice

Hazardous Material: No

Storage

Storage Temperature: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

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