REXO1 Antibody

REXO1 Antibody

Product Information

Product Overview:

REXO1 or Elongin A-binding protein 1 (EloA-BP1) is an exonuclease domain-containing protein that can bind to Elongin. The Elongin complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. REXO1 is composed of 1221 amino acids and its mRNA is ubiquitously expressed. EloA-BP1 is capable of binding not only the NH(2)-terminal approximately 120 amino acid region of Elongin A, but also that of SII. Although REXO1 had no detectable effect on the rate of transcription elongation in vitro, it may play some role in the regulation of elongation in vivo.

Catalog#: NBP1-31396
LID#: 171561A
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Specifications

Host SpeciesRabbit
SpeciesHuman
Entrez Human ID57455
LocalizationNucleus
NotesPlease note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.
Preservation0.01% Thimerosal
Species ReactivityTested in human. Not yet tested in any other species.
Gene SymbolREXO1
ApplicationsWB
Species AbbreviationHu
Grade/PurityAffinity purified
ClonalityPolyclonal
ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1037 and 1210 (Q8N1G1) of REXO1
Storage Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0).
DilutionWestern Blot 1:100-1:2000
Gene ID5617
Unit Size0.1mg
Concentration1.0 mg/ml
Safety StatementsThis product is for research use only and is not approved for use in humans or in clinical diagnosis.
Sample AvailabilityYes
SynonymEC 3.1, Elongin-A-binding protein 1, ELOABP1elongin A-binding protein 1, EloA-BP1REX1, KIAA1138elongin A binding protein 1, REX1, RNA exonuclease 1 homolog (S. cerevisiae), TCEB3BP1RNA exonuclease 1 homolog, transcription elongation factor B polypeptide 3 binding protein 1, Transcription elongation factor B polypeptide 3-binding protein 1

Shipping & Handling

Estimated Ship Time: 3 Business Days

Shipped In: Blue Ice

Hazardous Material: No

Storage

Storage Temperature: Store at -20C. Avoid freeze-thaw cycles.

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