Mre11 Antibody (1D8-A6)

Mre11 Antibody (1D8-A6)

Product Information

Product Overview:

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Application:

Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Catalog#: H00004361-M01
LID#: 171761A
Quantity :
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Specifications

Host SpeciesMouse
SpeciesHuman
Entrez Human ID4361
NotesThis product is produced by and distributed for Abnova, a company based in Taiwan.
PreservationNo Preservative
Species ReactivityHuman. Other species not tested.
Swissprot Human IDAAH05241
Gene SymbolMRE11A
ApplicationsWB, ELISA
Species AbbreviationHu
Grade/PurityIgG purified
Clone1D8-A6
ClonalityMonoclonal
ImmunogenMRE11A (AAH05241, 1 a.a. ~ 207 a.a) full length recombinant protein with GST tag.MSTADALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGDLFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISIPVFSIHGNHDDPTGADALCALDILSCAGFVNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDERLYRMFVNKKVTMLRPKED
SpecificityMRE11A - MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
IsotypeIgG2a Kappa
Storage BufferIn 1x PBS, pH 7.2
DilutionELISA, Western Blot 1:500
Gene ID399664
Unit Size0.1mg
Safety StatementsThis product is for research use only and is not approved for use in humans or in clinical diagnosis.
Sample AvailabilityYes
SynonymATLDmeiotic recombination (S. cerevisiae) 11 homolog A, AT-like disease, DNA recombination and repair protein, double-strand break repair protein MRE11A, endo/exonuclease Mre11, HNGS1, Meiotic recombination 11 homolog 1, Meiotic recombination 11 homolog A, MRE11 homolog 1, MRE11 homolog A, MRE11 meiotic recombination 11 homolog A (S. cerevisiae), MRE11MRE11B

Shipping & Handling

Estimated Ship Time: 3 Business Days

Shipped In: Blue Ice

Hazardous Material: No

Storage

Storage Temperature: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

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