MD2 Antibody (1A2E3)

MD2 Antibody (1A2E3)

Product Information

Product Overview:

MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.

Application:

MD-2 antibody can be used for detection of MD-2 by Western blot at 0.5 û 1 ug/mL

Catalog#: NBP1-75513
LID#: 171611A
Quantity :
Order by Phone or Fax: 1.800.316.3081

Specifications

Host SpeciesMouse
SpeciesHuman, Mouse, Rat
Entrez Human ID23643
Preservation0.02% Sodium Azide
Species ReactivityHuman, Mouse, Rat
Swissprot Human IDNP_056179
Gene SymbolLY96
ApplicationsWB, ELISA, IHC, IHC-P
Species AbbreviationHu, Mu, Rt
Grade/PurityImmunogen affinity purified
Clone1A2E3
ClonalityMonoclonal
ImmunogenAntibody was raised against a recombinant protein corresponding to amino acids 2 to 160 of human MD-2
Storage BufferPBS
DilutionELISA 1:100-1:2000, Immunohistochemistry 1:10-1:2000, Immunohistochemistry-Paraffin 2.5 ug/ml, Western Blot 0.5-1 ug/ml
Unit Size0.1mg
Safety StatementsThis product is for research use only and is not approved for use in humans or in clinical diagnosis.
Sample AvailabilityYes
SynonymESOP1, ESOP-1, ly-96, Ly-96, lymphocyte antigen 96, MD2, MD-2, myeloid differentiation protein-2, Protein MD-2

Shipping & Handling

Estimated Ship Time: 3 Business Days

Shipped In: Blue Ice

Hazardous Material: No

Storage

Storage Temperature: Store at 4C. Do not freeze.

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