MBD3 Antibody

MBD3 Antibody

Product Information

Product Overview:

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex. [provided by RefSeq]

Catalog#: NBP2-17235
LID#: 171794A
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Specifications

Host SpeciesRabbit
SpeciesHuman
Entrez Human ID53615
LocalizationNucleus
Preservation0.01% Thimerosal
Species ReactivityHuman. Species reactivity based on sequence identity: Mouse (96%), Chicken (96%), Monkey (100%), Rat (96%), Xenopus laevis (93%), Bovine (95%), Xenopus tropicalis (93%)
Swissprot Human IDO95983
TMW29 kDa
Gene SymbolMBD3
ApplicationsWB
Species AbbreviationHu
Grade/PurityImmunogen affinity purified
ClonalityPolyclonal
ImmunogenRecombinant fragment corresponding to a region within amino acids 20 and 260 of MBD3 (Uniprot ID#O95983)
Storage Buffer1XPBS, 1%BSA, 20% Glycerol (pH7).
DilutionWestern Blot 1:500-1:3000
Unit Size0.1ml
Concentration0.51 mg/ml
Safety StatementsThis product is for research use only and is not approved for use in humans or in clinical diagnosis.
Sample AvailabilityYes
Synonymmethyl-CpG binding domain protein 3, methyl-CpG-binding domain protein 3, Methyl-CpG-binding protein MBD3

Shipping & Handling

Estimated Ship Time: 3 Business Days

Shipped In: Blue Ice

Hazardous Material: No

Storage

Storage Temperature: Store at -20C. Avoid freeze-thaw cycles.

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