MAS1 Antibody [DyLight 650]

MAS1 Antibody [DyLight 650]

Product Information

Product Overview:

MAS1 oncogene (Proto-oncogene Mas, MAS1) is a GTP binding protein coupled receptor which shares a conserved structural motif with other proteins of its class. When activated, MAS1 is a modulator of a critical step in the growth-regulating pathway to trigger oncogenes (PMID: 20674894). Evidence has shown that the MAS1 oncogene acts as a receptor for angiotensin (Ang)-(1-7), however it is not fully known how Intracellular signaling through Mas1 occurs (PMID: 19461648). Furthermore, research proves that in tandom with Ang-(1-7), the MAS1 receptor is expressed in the ovarian stroma of post menopausal women and in male testis (PMID: 20674894, 20361351). Additionally, together with Ang- (1-7) MAS1 may be an important component of normal spermatogenesis as low expression levels were found in infertile men with impaired spermatogenesis (PMID: 20361351).

Application:

This MAS1 antibody is useful for Immunohistochemistry-Paraffin. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

Catalog#: NLS1531C
LID#: 171627A
Quantity :
Order by Phone or Fax: 1.800.316.3081
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Specifications

Host SpeciesRabbit
SpeciesHuman, Mouse
Entrez Human ID4142
LocalizationCell membrane
PreservationNo Preservative
Species ReactivityReacts with human and mouse. 82% sequence identity with rat proteins.
Gene SymbolMAS1
ApplicationsICC/IF, IHC, IHC-P
Species AbbreviationHu, Mu
Grade/PurityImmunogen affinity purified
ClonalityPolyclonal
ImmunogenSynthetic peptide [KLH conjugated] made to the C-terminus of human protein.
ConjugationDyLight 650
SpecificityMas Proto-Oncogene
Storage Buffer50 mM sodium borate
DilutionImmunocytochemistry/Immunofluorescence 1:10-1:2000, Immunohistochemistry 1:100-1:500, Immunohistochemistry-Paraffin 1:100-1:500
Unit Size0.05ml
Concentration1 mg/ml
Safety StatementsThis product is for research use only and is not approved for use in humans or in clinical diagnosis.
Sample AvailabilityYes
SynonymMAS, MAS1 oncogene, MGC119966, proto-oncogene Mas

Shipping & Handling

Estimated Ship Time: 3 Business Days

Shipped In: Blue Ice

Hazardous Material: No

Storage

Storage Temperature: Store at 4C in the dark.

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