MAPKAP Kinase 3 Antibody

MAPKAP Kinase 3 Antibody

Product Information

Product Overview:

This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.

Catalog#: NBP1-68068-0.1mg
LID#: 171526A
Quantity :
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Specifications

Host SpeciesRabbit
SpeciesHuman, Mouse, Rat
Entrez Human ID7867
Preservation0.02% Sodium Azide
Species ReactivityHuman,Mouse, Rat
Swissprot Human IDQ16644
Gene SymbolMAPKAPK3
ApplicationsWB, ELISA, IHC, IHC-P
Species AbbreviationHu, Mu, Rt
Grade/PurityImmunogen affinity purified
ClonalityPolyclonal
ImmunogenThe antiserum was produced against synthesized peptide derived from human MAPK3. The immunogen region is: C-terminal.
SpecificityMAPK3 Antibody detects endogenous levels of total MAPK3 protein.
Storage Bufferphosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, and 50% glycerol.
DilutionELISA 1:20000, Immunohistochemistry 1:50-1:100, Immunohistochemistry-Paraffin 1:50-1:100, Western Blot 1:500-1:1000
Unit Size0.1mg
Concentration1 mg/ml
Safety StatementsThis product is for research use only and is not approved for use in humans or in clinical diagnosis.
Sample AvailabilityYes
Synonym3PKEC 2.7.11.1, Chromosome 3p kinase, EC 2.7.11, MAP kinase-activated protein kinase 3, MAPKAP33pK, MAPKAPK-3, MAPK-activated protein kinase 3, MAPKAP kinase 3, mitogen-activated protein kinase-activated protein kinase 3

Shipping & Handling

Estimated Ship Time: 3 Business Days

Shipped In: Blue Ice

Hazardous Material: No

Storage

Storage Temperature: Store at -20C. Avoid freeze-thaw cycles.

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