Lck Antibody (8E5F9)

Lck Antibody (8E5F9)

Product Information

Product Overview:

Lck(lymphocyte-specific protein tyrosine kinase), with 509-amino acid protein (about 56kDa), belongs to the Src non-receptor tyrosine kinases family. By virtue of common structural motifs, the Src family is composed of nine members in vertebrates, including Src, Yes, Fgr, Frk, Fyn, Lyn, Hck, Lck and Blk. Lck is expressed predominantly in T cells and is localized to the inner surface of the plasma membrane. Lck is activated after T cell stimulation and is required for T-cell proliferation and IL-2 production. Aberrant expression or activation of Lck kinase has been reported in both lymphoid and nonlymphoid malignancies. In addition, inhibition of Lck has been a target to prevent lymphocyte activation and acute rejection.

Catalog#: NB110-60496
LID#: 171685A
Quantity :
Order by Phone or Fax: 1.800.316.3081

Specifications

Host SpeciesMouse
SpeciesHuman
Entrez Human ID3932
Modificationp Ser41
Preservation0.03% Sodium Azide
Species ReactivityHuman
Gene SymbolLCK
ApplicationsWB, ELISA
Species AbbreviationHu
Grade/PurityAscites
Clone8E5F9
ClonalityMonoclonal
ImmunogenNi-NTA purified truncated recombinant Lck expressed in E. Coli strain BL21 (DE3)
SpecificityLck (8E5F9)
IsotypeIgG2a
DilutionELISA 1: 10000, Western Blot 1: 500-1: 2000
Gene ID4704
Unit Size0.1ml
Safety StatementsThis product is for research use only and is not approved for use in humans or in clinical diagnosis.
Sample AvailabilityYes
SynonymEC 2.7.10, EC 2.7.10.2, Leukocyte C-terminal Src kinase, LSK, Lymphocyte cell-specific protein-tyrosine kinase, lymphocyte-specific protein tyrosine kinase, p56(LSTRA) protein-tyrosine kinase, p56lck, p56-LCK, pp58lck, proto-oncogene tyrosine-protein kinase LCK, Proto-oncogene Lck, Protein YT16, T cell-specific protein-tyrosine kinase, T-lymphocyte specific protein tyrosine kinase p56lck, tyrosine-protein kinase Lck, YT16

Shipping & Handling

Estimated Ship Time: 3 Business Days

Shipped In: Blue Ice

Hazardous Material: No

Storage

Storage Temperature: Store at -20C. Avoid freeze-thaw cycles.

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