LITAF Antibody

LITAF Antibody

Product Information

Product Overview:

Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

Catalog#: NBP1-32726
LID#: 171616A
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Specifications

Host SpeciesRabbit
SpeciesHuman
Entrez Human ID9516
LocalizationLysosome membrane, Peripheral membrane protein, Cytoplasmic side
Preservation0.01% Thimerosal
Species ReactivityTested in human. Not yet tested in any other species.
Gene SymbolLITAF
ApplicationsWB
Species AbbreviationHu
Grade/PurityAffinity purified
ClonalityPolyclonal
ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 161 of LITAF (Uniprot ID#Q99732)
Storage Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0).
DilutionWestern Blot 1:500-1:3000
Gene ID10741
Unit Size0.1mg
Concentration1.0 mg/ml
Safety StatementsThis product is for research use only and is not approved for use in humans or in clinical diagnosis.
Sample AvailabilityYes
SynonymCMT1C, FLJ38636, lipopolysaccharide-induced TNF factor, lipopolysaccharide-induced TNF-alpha factor, lipopolysaccharide-induced tumor necrosis factor-alpha factor, LPS-induced TNF-alpha factor, MGC116698, MGC116700, MGC125275, MGC125276, p53-induced gene 7 protein, PIG7MGC116701, SIMPLEMGC125274, Small integral membrane protein of lysosome/late endosome, TP53I7, tumor protein p53 inducible protein 7

Shipping & Handling

Estimated Ship Time: 3 Business Days

Shipped In: Blue Ice

Hazardous Material: No

Storage

Storage Temperature: Store at -20C. Avoid freeze-thaw cycles.

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