LDB3 Antibody

LDB3 Antibody

Product Information

Product Overview:

This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1 and 2) have C-terminal LIM domains. [provided by RefSeq]

Application:

Antibody reactive against transfected lysate and tissue lysate for Western Blot. Has also been used for immunofluoresence and ELISA.

Catalog#: H00011155-B01
LID#: 171712A
Quantity :
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Specifications

Host SpeciesMouse
SpeciesHuman
Entrez Human ID11155
NotesThis product is produced by and distributed for Abnova, a company based in Taiwan.
PreservationNo Preservative
Species ReactivityHuman. Other species not tested.
Swissprot Human IDNP_001073585.1
Gene SymbolLDB3
ApplicationsWB, ELISA, ICC/IF
Species AbbreviationHu
Grade/PurityWhole antisera
ClonalityPolyclonal
ImmunogenLDB3 (1 a.a. ~ 283 a.a) full-length human protein.MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQERFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDFSGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRERF
SpecificityLDB3 - LIM domain binding 3,
Storage BufferThis is unpurified antiserum so it is not possible to supply the specific antibody concentration.
DilutionELISA, Western Blot 1:500, Immunocytochemistry/Immunofluorescence
Gene ID2193
Unit Size0.05ml
Safety StatementsThis product is for research use only and is not approved for use in humans or in clinical diagnosis.
Sample AvailabilityYes
SynonymCMD1C, CYPHER, KIAA0613FLJ35865, KIAA01613, LDB3Z1, LDB3Z4, LIM domain-binding protein 3, LIM domain binding 3, ORACLE, PDLIM6, PDZ and LIM domain 6, Protein cypher, ZASPLVNC3, Z-band alternatively spliced PDZ-motif protein

Shipping & Handling

Estimated Ship Time: 3 Business Days

Shipped In: Blue Ice

Hazardous Material: No

Storage

Storage Temperature: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

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