LCAT Antibody

LCAT Antibody

Product Information

Product Overview:

Lecithin: cholesterol acyltransferase (LCAT) is the plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP) it is also responsible for a significant proportion of VLDL and LDL cholesteryl esters. LCAT, through the esterification of cholesterol, plays a role in the reverse cholesterol transport pathway by facilitating the net movement of cholesterol from peripheral tissues back to the liver for excretion. LCAT deficiency results in low levels of plasma HDL, whereas a transgenic overexpression of LCAT results in increased plasma HDL concentrations.

Application:

This LCAT antibody may be used in ELISA and Western blot, where a band is seen at 62-65 kDa representing LCAT. This antibody does exhibit neutralizing activity for cholesterol esterification.

Catalog#: NB400-107
LID#: 171672A
Quantity :
Order by Phone or Fax: 1.800.316.3081
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Specifications

Host SpeciesRabbit
SpeciesHuman, Mouse
ControlsAntigen standard for LCAT (NM_000229) (transient overexpression lysate), Lipoprotein fraction of whole human plasma (albumin has the same ~MW as LCAT. Also affinity purifie
Entrez Human ID3931
Preservation0.05% Sodium Azide
Species ReactivityHuman and Mouse.
Swissprot Human IDP04180
Gene SymbolLCAT
ApplicationsWB, ELISA
Species AbbreviationHu, Mu
Grade/PurityWhole antisera
ClonalityPolyclonal
ImmunogenCarboxyl-terminal histidine-tagged human recombinant LCAT purified from the medium of CHO cells overexpressing human LCAT cDNA. [UniProt# P04180]
DilutionELISA 2 ug/ml, Western Blot 1:1000
Gene ID10936
Unit Size0.1ml
Safety StatementsThis product is for research use only and is not approved for use in humans or in clinical diagnosis.
Sample AvailabilityYes
SynonymEC 2.3.1.43, lecithin-cholesterol acyltransferasePhospholipid-cholesterol acyltransferase, phosphatidylcholine-sterol acyltransferase

Shipping & Handling

Estimated Ship Time: 3 Business Days

Shipped In: Blue Ice

Hazardous Material: No

Storage

Storage Temperature: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

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