LATS2 Antibody

LATS2 Antibody

Product Information

Product Overview:

This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.

Catalog#: NB200-199
LID#: 171581A
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Host SpeciesRabbit
SpeciesHuman, Mouse
ControlsAntigen standard for LATS2 (NM_014572) (transient overexpression lysate), Hela Whole Cell Extract NB800-PC1
Entrez Human ID26524
Preservation0.09% Sodium Azide
Species ReactivityBased on 100% sequence identity, this antibody is predicted to react with Rat, X. tropicalis, Chicken, Turkey, Bovine, Dog, Horse, Rabbit, Guinea pig_10141, Pig, Panda, Orangutan, Gorilla, Chimpanzee, Duckbill platypus, Tasmanian devil, White-tufted-ear marmoset and Northern white-cheeked gibbon.
Swissprot Human IDQ9NRM7
Gene SymbolLATS2
ApplicationsWB, IP, PLA
Species AbbreviationHu, Mu
Grade/PurityImmunogen affinity purified
ImmunogenThe immunogen recognized by this antibody maps to a region between residues 1 and 50 of human Large Tumor Suppressor 2 using the numbering given in entry NP_055387.1 (GeneID 26524).
Storage BufferTris-citrate/phosphate buffer, pH 7 to 8
DilutionImmunoprecipitation 2-5 ug/mg lysate, Proximity Ligation Assay 1:1000 - 1:20000, Western Blot 1:1000-1:5000
Gene ID30009
Unit Size0.1ml
Concentration1.0 mg/ml
Safety StatementsThis product is for research use only and is not approved for use in humans or in clinical diagnosis.
Sample AvailabilityYes
SynonymEC 2.7.11, EC, FLJ13161, KPM, Kinase phosphorylated during mitosis protein, LATS (large tumor suppressor, Drosophila) homolog 2, LATS, large tumor suppressor, homolog 2 (Drosophila), Large tumor suppressor homolog 2, serine/threonine kinase KPM, Serine/threonine-protein kinase kpm, serine/threonine-protein kinase LATS2, Warts-like kinase

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Hazardous Material: No


Storage Temperature: Store at 4C. Do not freeze.

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