B Raf Antibody (3C6)

B Raf Antibody (3C6)

Product Information

Product Overview:

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq]

Application:

Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Catalog#: H00000673-M01A
LID#: 171544A
Quantity :
Order by Phone or Fax: 1.800.316.3081

Specifications

Host SpeciesMouse
SpeciesHuman
Entrez Human ID673
NotesThis product is produced by and distributed for Abnova, a company based in Taiwan.
PreservationNo Preservative
Species ReactivityHuman.
Swissprot Human IDNP_004324
Gene SymbolBRAF
ApplicationsWB, ELISA, S-ELISA
Species AbbreviationHu
Grade/PurityAscites
Clone3C6
ClonalityMonoclonal
ImmunogenBRAF (NP_004324, 346 a.a. ~ 445 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.FRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRD
SpecificityBRAF - v-raf murine sarcoma viral oncogene homolog B1 (3C6)
IsotypeIgM Kappa
Storage BufferIn ascites fluid
DilutionSandwich ELISA, ELISA, Western Blot 1:500
Gene ID53615
Unit Size0.2ml
Safety StatementsThis product is for research use only and is not approved for use in humans or in clinical diagnosis.
Sample AvailabilityYes
Synonym94 kDa B-raf protein, B-Raf proto-oncogene serine/threonine-protein kinase (p94), B-RAF1, BRAF1MGC126806, EC 2.7.11.1, MGC138284, murine sarcoma viral (v-raf) oncogene homolog B1, NS7, p94, Proto-oncogene B-Raf, RAFB1, serine/threonine-protein kinase B-raf, v-raf murine sarcoma viral oncogene homolog B1FLJ95109

Shipping & Handling

Estimated Ship Time: 3 Business Days

Shipped In: Blue Ice

Hazardous Material: No

Storage

Storage Temperature: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

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