anti-human Rad51 antibody, rabbit s...

anti-human Rad51 antibody, rabbit serum

As One International, Inc.

Product Information

Product Overview:

Human Rad51 protein is a functional and structural homolog of E. coli RecA protein, which plays a major role in genetic recombination and recombination repair by mediating strand exchange reaction between homologous DNA strands. Rad51 functionally and physically interacts with its paralogs Dmc1, Rad51B, Rad51C, Rad51D, Xrcc2 and Xrcc3, and also with Rad52 in recombination processes. It also interacts with oncogenes and tumor suppressors such as BRACA1, BRACA2, and P53 for the maintenance of genome stability.    The product was prepared by immunizing rabbit with full-size recombinant Rap51 protein expressed in E. coli and purified.    Using this anti-serum, Rad51 protein (37 kD) in the crude extract of Hela cells was detected by Western blotting and Rad51 foci formation induced by stalled replication and DNA-damage was detected by indirect immunofluorescence. GFP-tagging of Rap51 protein at either N- or C- terminus inactivates the function of Rad51 and, therefore, it cannot be used for the study of foci formation instead of the antibody.

Application:

WB, IP, IF

Catalog#: 70-001
LID#: 3163A
Quantity :
Order by Phone or Fax: 1.800.316.3081
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Specifications

ClonalityPolyclonal
Raised InRabbit
ReactivityHuman, Mouse Chicken
Gene IDQ06609
Unit Size50 ul
Safety StatementsThis product is for research use only.
Sample AvailabilityNo

Shipping & Handling

Estimated Ship Time: 3 Business Days

Shipped In: Blue Ice

Hazardous Material: No

Storage

Storage Temperature: See datasheet

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